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For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Restriction enzymes, modifying enzymes, buffering solutions, inhibitors, and substrates for use in clinical, research, and general laboratory procedures.
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An active metabolite of thalidomide and a PROTAC synthetic intermediate; decreases production of TNF-α induced by TPA in THP-1 cells at 30 µM; completely inhibits the proliferation HUVECs at 333 µM; inhibits VEGF- and FGF2-induced angiogenesis by 14% in a CAM assay in utero at 100 UG/embryo
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Let Fadeless Bulletin Board Art Paper spark your bulletin board ideas. Create fun and inviting classrooms with this premier, ultra fade-resistant paper. Use on bulletin boards, doors, file cabinets, backdrops, 3D paper sculptures and more. Durable construction and acid-free qualities create long-lasting displays. Recyclable paper on convenient rolls is perfect for school, home and office projects.
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Prepared from the 1 mM sodium pyrophosphate, pH 6.9, alumina gel eluate of Hilmoe, Biochem. Prep, 8, (Meister, A., ed.), John Wiley & Sons, NY, NY, p. 105 (1961). Lyophilized in vials. 9068-54-6
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Glycerol-Free T4 DNA Ligase (HC) a glycerol-free, high concentration enzyme (50U/uL) that catalyzes the formation of a phosphodiester bond between adjacent 5ʹ phosphate and 3′ hydroxyl groups in duplex DNA or RNA. The enzyme efficiently joins blunt and sticky-ended fragments in just 15 and 10 minutes respectively at room temperature (25C). It can be used to perform linker ligation, re-ligation of linearized plasmids and ligation of double-stranded oligonucleotides into vectors and enables rapid ligation of up to 100ng of fragments from most sources including PCR fragments, plasmids, cosmids, genomic, phage and viral DNA into prokaryotic or eukaryotic plasmid vectors and bacteriophage lambda vectors.
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This gene encodes a DNA topoisomerase an enzyme that controls and alters the topologic states of DNA during transcription This nuclear enzyme is involved in processes such as chromosome condensation chromatid separation and the relief of torsional stress that occurs during DNA transcription and replication It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another thus altering the topology of DNA Two forms of this enzyme exist as likely products of a gene duplication event The gene encoding this form alpha is localized to chromosome 17 and the beta gene is localized to chromosome 3 The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance Reduced activity of this enzyme may also play a role in ataxia-telangiectasia
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The Fish Catalase (CAT) ELISA Kit is designed for the quantitative detection of catalase (CAT) in fish serum and plasma samples using a competitive ELISA method This kit detects CAT within a broad dynamic range of 125 mU/mL to 2000 mU/mL with a sensitivity of 62 5 mU/mL ensuring precise measurement of enzyme activity The assay requires a short incubation period of 1 to 5 hours and utilizes a minimal sample volume of 50-100 L per test Optical density readings are performed at 450 nm providing reliable and reproducible results for research applications Ideal for studying oxidative stress biomarkers this kit offers a robust and efficient tool for quantifying CAT levels in aquatic species
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